White dung • 60 capsules

Description

Pharmacological and medical properties

The fungus has pronounced anti-cancer, antioxidant, antibacterial, antifungal, hepatoprotective and antidiabetic activity. Recently, neuroprotective properties have also been recorded for it.

The extract from fresh mushrooms showed complete suppression of test sarcoma-180 and Ehrlich carcinoma. Compounds that stop the growth of breast cancer cell culture have been identified. Alcohol extracts, even in small doses, kill ovarian cancer cells and stop prostate cancer. The antibiotic coprinin contained in white dung is active against pathogenic molds, fungi and bacteria (Aspergillus niger, Candida albicans, Esherichia coli, Staphylococcus, Pseudomonas and Bacillus). The enzymatically obtained coprinol is active against many types of gram-positive bacteria resistant to most modern drugs. Data have been obtained that polysaccharides of white dung contribute to the work of the enzyme lysozyme produced by the body, which damages the cell wall of pathogenic bacteria.

Studies of the last decade have shown that dung preparations rich in vanadium reduce blood sugar levels and, accordingly, can be used as antidiabetic. Mushroom extract with vanadium reduces glucose levels (including adrenaline) stabilizes glycohemoglobin and increases overall glucose resistance. The isolated polysaccharide komatin also increases overall glucose resistance and lowers cholesterol and triglycerides. The aqueous extract of the deep mycelial culture of white dung showed high antioxidant activity. This is due to the presence of ergothionine, one of the fungal amino acids.

The lipids contained in white dung (represented mainly by unsaturated fatty acids) contribute to the stabilization of cholesterol levels in the blood and prevent the development of atherosclerosis. In Asian official medicine, dung is used as an adjunct in the treatment of diabetes. Chromium-enriched gel from fresh mushroom helps to reduce blood sugar levels.

Clinical experiments have shown that the mushroom is especially useful for improving the vital signs of the elderly and children, and also contributes to the normal development of the fetus during pregnancy. Regular consumption of white dung strengthens the immune system, increasing the nonspecific immunological response of the body.

Fungotherapy

In China, it is used to treat hemorrhoids (resorption of hemorrhoids) and normalize digestion (it is believed that white dung stimulates and stabilizes the gastrointestinal tract).

At home, the optimal use of dried white dung should be considered either simply cooking as part of various mushroom dishes (soups, broths, roasts, etc.), or in the form of an aqueous infusion in the proportion of 1 tablespoon of roughly ground fruit bodies per glass of boiling water, which is infused in a thermos for 2-3 hours. For a pronounced effect in all cases, regular, fairly long-term use is necessary (2-3 times a week for 3-6 months).

What serious read on topic

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Li B, Lu F, Suo X, Nan H, Li B. Antioxidant properties of cap and stipe from Coprinus comatus. Molecules. 2010;15(3):1473-1486. Published 2010 Mar 9. doi:10.3390/molecules15031473

Rouhana-Toubi A, Wasser SP, Fares F. The Shaggy Ink Cap Medicinal Mushroom, Coprinus comatus (Higher Basidiomycetes) Extract Induces Apoptosis in Ovarian Cancer Cells via Extrinsic and Intrinsic Apoptotic Pathways. Int J Med Mushrooms. 2015;17(12):1127-1136. doi:10.1615/intjmedmushrooms.v17.i12.20

Stojković D, Reis FS, Barros L, et al. Nutrients and non-nutrients composition and bioactivity of wild and cultivated Coprinus comatus (O.F.Müll.) Pers. Food Chem Toxicol. 2013;59:289-296. doi:10.1016/j.fct.2013.06.017

Tešanović K, Pejin B, Šibul F, et al. A comparative overview of antioxidative properties and phenolic profiles of different fungal origins: fruiting bodies and submerged cultures of Coprinus comatus and Coprinellus truncorum. J Food Sci Technol. 2017;54(2):430-438. doi:10.1007/s13197-016-2479-2

Xu N, Zhang T, Chen X, Zhang H, Wang R. Sheng Wu Gong Cheng Xue Bao. 2017;33(5):808-816. doi:10.13345/j.cjb.160440

Zhang P, Li K, Yang G, et al. Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity. Proc Natl Acad Sci U S A. 2017;114(34):8980-8985. doi:10.1073/pnas.1706894114

Zhao H, Li H, Lai Q, et al. Antioxidant and hepatoprotective activities of modified polysaccharides from Coprinus comatus in mice with alcohol-induced liver injury. Int J Biol Macromol. 2019;127:476-485. doi:10.1016/j.ijbiomac.2019.01.067

Zhao H, Zhang J, Liu X, Yang Q, Dong Y, Jia L. The antioxidant activities of alkalic-extractable polysaccharides from Coprinus comatus on alcohol-induced liver injury in mice. Sci Rep. 2018;8(1):11695. Published 2018 Aug 3. doi:10.1038/s41598-018-30104-6

Vishnevsky M. V. Medicinal mushrooms of Russia. Moscow: Prospect, 2017.